Effect of Preemptive Analgesia on Pain Perception in Children: A Randomized Controlled Trial

Mira Virda1, Anup Panda1, Kanu Kataria2

  • 1Department of Pediatric and Preventive Dentistry, College of Dental Sciences and Research Centre, Ahmedabad, Gujarat, India.

Insights

Preemptive analgesia with Ibugesic Plus significantly reduced pain during and after primary tooth extraction in children. This approach offers a rational strategy for pediatric dental pain management, improving patient experience.

Area of Science:

  • Pediatric Dentistry
  • Pain Management
  • Anesthesiology

Background:

  • Minimizing pain and needle fear in children undergoing dental procedures is crucial.
  • Positive experiences are essential for pediatric dental patients.
  • This study evaluates premedication with Ibugesic Plus for local anesthesia and extraction in children.

Purpose of the Study:

  • To assess the efficacy of preemptive analgesia in managing pain during local anesthesia administration and extraction.
  • To evaluate the impact of Ibugesic Plus on pain perception in pediatric patients.
  • To compare pain levels between children receiving preemptive analgesia and a placebo.

Main Methods:

  • A randomized controlled trial involving 104 children aged 7-10 years requiring primary molar extraction.
  • Group I received Ibugesic Plus syrup 30 minutes before extraction; Group II received a placebo (B-Folcin syrup).
  • Pain levels, pulse rate, and SpO2 were measured using the Wong-Baker Faces Pain Rating Scale and pulse oximeter post-injection, post-extraction, and postoperatively.

Main Results:

  • Pain scores were highest immediately after injection and extraction.
  • Children receiving preemptive analgesics (Group I) reported significantly lower pain scores compared to the placebo group (Group II).
  • Pain reduction was observed immediately after injection, after extraction, and 2 hours postoperatively.

Conclusions:

  • Preemptive analgesic administration, such as with Ibugesic Plus, is an effective pain management strategy for primary tooth extractions.
  • This approach can be considered a routine and rational method for managing pain in pediatric dental procedures.
  • Preemptive analgesia can reduce postoperative pain in children undergoing dental treatments.
Abstract

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
547
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
239
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
107
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
421