Detecting expressed genes in cell populations at the single-cell level with scGeneXpress

Sascha Jung1, Céline Barlier2, Aitor Martinez Perez1

  • 1Computational Biology Group, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Parque Cientifico Tecnologico de Bizkaia 801A, 48160 Derio, Spain.

PubMed

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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