Paget's Disease Mimicking Prostate Cancer Metastasis with ⁶⁸Ga-PSMA PET/CT

⁶⁸Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography imaging successfully detects bone metastases in prostate cancer (PCa). However, assuming that all detected PSMA-avid bone lesions are metastases should be avoided. It is essential to evaluate PCa patients with clinical findings and to consider possible differential diagnoses, especially in low-risk patients. Herein, we present the case of a 62-year-old male patient recently diagnosed with low-risk prostate adenocarcinoma with a PSMA-avid bone lesion corresponding to Paget's disease.