Related Experiment Video
Updated: Jun 11, 2025
07:12
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
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Intrathyroidal Parathyroid Adenoma
Sara Zouggari1, Mohamed Aziz Bsiss1, Aboubaker Matrane1
1Mohammed VI University Hospital, Department of Nuclear Medicine, Marrakesh, Morocco.
Molecular Imaging and Radionuclide Therapy
|October 7, 2024
Summary
Intrathyroidal parathyroid adenoma, a rare cause of hyperparathyroidism treatment failure, was diagnosed using MIBI scintigraphy. Surgical removal led to normalized laboratory results, confirming the imaging modality
Area of Science:
- Endocrinology
- Surgical Pathology
- Nuclear Medicine
Background:
- Intrathyroidal parathyroid adenoma is a rare anomaly, occurring in 1.4-6% of cases.
- Ectopic parathyroid adenoma localization, especially intrathyroidal, can lead to therapeutic failure in hyperparathyroidism management.
Purpose of the Study:
- To report a case of intrathyroidal parathyroid adenoma.
- To highlight the diagnostic utility of MIBI scintigraphy in identifying ectopic parathyroid tissue.
Main Methods:
- Case presentation of a 51-year-old patient with neck pain and goiter.
- Diagnostic imaging using Technetium-99m sestamibi (MIBI) scintigraphy.
- Surgical intervention via left loboishmectomy and subsequent histopathological analysis.
Main Results:
- MIBI scintigraphy identified an ectopic focus consistent with parathyroid origin.
- Histopathology confirmed parathyroid adenoma coexisting with dystrophic thyroid parenchyma.
- Post-surgical normalization of laboratory work-up.
Conclusions:
- Intrathyroidal parathyroid adenoma, though uncommon, is a significant cause of treatment failure in hyperparathyroidism.
- MIBI scintigraphy is the gold standard for diagnosing parathyroid ectopy, including intrathyroidal locations.
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