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Luminescence Modulation in Boron-Cluster-Based Luminogens via Boron Isotope Effects
Wenli Ma1, Jianyu Zhang2, Jibo Zong1
1State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Angewandte Chemie (International Ed. in English)
|October 7, 2024
Summary
Boron isotope effects significantly impact luminescent materials. Enriched 11B carboranes enhance luminescence efficiency and thermal stability, showing potential for optoelectronic and biomedical applications like boron neutron capture therapy.
Area of Science:
- Materials Science
- Photophysics
- Organic Chemistry
Background:
- Hydrogen isotope effects are known to influence optoelectronic properties of luminescent materials.
- Research on boron isotope effects in photophysical properties of organic luminogens is underdeveloped.
Purpose of the Study:
- To explore the influence of boron isotope effects on the photophysical properties of boron-cluster-based luminogens.
- To investigate the potential applications of these materials in optoelectronics and biomedicine.
Main Methods:
- Design and synthesis of carborane-based luminogens enriched with 10B and 11B isotopes.
- Characterization of photophysical properties including luminescence efficiency, emission lifetime, and spectral width.
- Evaluation of thermal stability and electrochemiluminescence.
- Biological assessments of 10B-enriched luminogens for cytotoxicity and imaging capabilities.
Main Results:
- 11B-enriched luminogens exhibited enhanced luminescence efficiency, prolonged emission lifetime, and reduced spectral width compared to 10B-enriched counterparts.
- Increased thermal stability, redshifted B-H vibrations, and a fourfold increase in electrochemiluminescence intensity were observed with 11B enrichment.
- 10B-enriched luminogens showed low cytotoxicity, high boron uptake, and effective fluorescence imaging, indicating potential for boron neutron capture therapy (BNCT).
Conclusions:
- This study provides the first comprehensive exploration of boron isotope effects in boron clusters.
- Boron isotope manipulation offers a valuable strategy for designing organic luminogens with improved optoelectronic and biomedical properties.
- The findings pave the way for advanced applications in fields ranging from lighting to targeted cancer therapy.
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