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Castleman's Disease Mimicking Malignant Submandibular Tumor: A Case Report
Jihene Houas1, Monia Ghammam1, Maroua Naouar1
1ENT Department and Cervical Surgery Farhat Hached Hospital, Medicine University, Sousse, Tunisia.
Summary
A 71-year-old man with submandibular swelling was diagnosed with unicentric Castleman's disease. This rare condition mimicked malignancy, highlighting the importance of histological examination for accurate diagnosis of neck masses.
Area of Science:
- Head and Neck Surgery
- Pathology
- Oncology
Background:
- Submandibular masses present a diagnostic challenge with diverse potential causes.
- Neck swelling can be indicative of various benign or malignant conditions requiring thorough investigation.
Purpose of the Study:
- To report a rare case of unicentric Castleman's disease presenting as a submandibular mass.
- To emphasize the differential diagnosis of submandibular swellings, particularly when malignancy is suspected.
Main Methods:
- Clinical presentation of a 71-year-old male with left submandibular swelling and lymphadenopathy.
- Diagnostic workup including imaging and laboratory investigations.
- Histopathological examination for definitive diagnosis.
Main Results:
- Initial investigations suggested a malignant submandibular tumor.
- Final histological examination confirmed unicentric Castleman's disease.
- The patient's presentation mimicked a malignant neoplasm.
Conclusions:
- Unicentric Castleman's disease should be considered in the differential diagnosis of submandibular masses, especially when clinical and initial investigations are suggestive of malignancy.
- Histological confirmation is crucial for differentiating Castleman's disease from other neoplastic processes in the head and neck region.
