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Updated: Jun 11, 2025

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Published on: February 28, 2019
Biphenotypic Sinonasal Sarcoma- A case Series with a Review of Literature
Anubhuti Chaturvedi1, Gauri Kumari1, Nimisha Dhankar1
1Department of Pathology, Pathology Block, Maulana Azad Medical College and Lok Nayak Hospital, Room 57, New Delhi, 110002 India.
Abstract:
Biphenotypic sinonasal sarcoma (BSNS) is a rare malignant tumor that affects the upper nasal cavity and ethmoid sinuses. It is more commonly found in middle-aged women and is characterized by the infiltration and hypercellular proliferation of spindle cells. These cells exhibit specific immunoreactivity. We add seven cases diagnosed as BSNS, to the handful of cases already available in the literature.BSNS is a malignant disease of the sinonasal tract that requires prompt and accurate diagnosis, followed by surgical resection and consideration of radiotherapy. Our analysis of seven cases supports previous research that confirms the aggressive nature of the disease but also shows that it is treatable with the right approach.

