Related Experiment Video
Updated: Jun 11, 2025

08:19
Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
Published on: May 5, 2022
2.4K
In Response to: “Involvement of the Endocrine System is Common in Mitochondrial Disorders and Requires Long-term
Esra Deniz Papatya Çakır1, Melike Ersoy1, Nihan Çakır Biçer2
1University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Pediatric Nutrition and Metabolism, İstanbul, Turkey
Journal of Clinical Research in Pediatric Endocrinology
|October 8, 2024
Abstract
No abstract available in PubMed .
Related Concept Videos
Mitochondrial Membranes
9.1K
A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...
9.1K
Electron Transport Chain: Complex I and II
12.1K
The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
ROS generation is regulated and maintained at moderate levels necessary...
12.1K

