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Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Updated: Jun 11, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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Multiparameter MRI features of prostatic malakoplakia.

Han-Jiang Zeng1, Ling Yang1, Jin Yao1

  • 1Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.

The British Journal of Radiology
|October 8, 2024
PubMed
Summary

Multiparameter MRI (mpMRI) can identify prostatic malakoplakia. Diffuse, symmetrical peripheral zone lesions with preserved margins and delayed enhancement are characteristic, helping differentiate from cancer.

Keywords:
Prostate Imaging-Reporting and Data Systemgranulomatous prostatitismultiparameter MRIprostatic malakoplakia

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Area of Science:

  • Radiology
  • Uropathology
  • Oncology

Background:

  • Prostatic malakoplakia is a rare inflammatory condition.
  • Distinguishing it from prostate cancer on imaging is crucial for appropriate management.

Purpose of the Study:

  • To summarize the multiparameter MRI (mpMRI) features of pathologically confirmed prostatic malakoplakia.
  • To identify imaging characteristics that can help differentiate malakoplakia from prostate cancer.

Main Methods:

  • Retrospective review of mpMRI features in eleven patients with confirmed prostatic malakoplakia.
  • Analysis of lesion distribution, signal intensity on T1- and T2-weighted images, and enhancement patterns.

Main Results:

  • Lesions typically presented with PI-RADS scores of 4 or 5, involving the peripheral zone.
  • Characteristic findings included diffuse, symmetrical distribution, bulging/compression of the capsule without infiltration, moderate T2 hypointensity, slight T1 hyperintensity, and delayed periprostatic enhancement.

Conclusions:

  • Diffuse, symmetrical peripheral zone distribution with preserved capsule and margin, along with slight T1 hyperintensity and delayed periprostatic enhancement, are key features suggesting malakoplakia.
  • These mpMRI findings aid in differentiating prostatic malakoplakia from prostate cancer.