Related Experiment Video
Updated: Jul 24, 2026

10:50
Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
12.9K
Multiple sporadic schwannomas in a previously radiated field
Jeffrey Rosenthal1, Chukwuemeka Okoro1, Naomi Walker1
1Department of Radiological Sciences, UCLA Health System, Los Angeles, CA, USA.
Radiology Case Reports
|October 9, 2024
Summary
Multiple benign schwannomas developed in an irradiated area in a patient with a history of testicular cancer. This rare occurrence highlights the potential for secondary tumor development following radiation therapy.
Area of Science:
- Oncology
- Neuropathology
- Radiation Oncology
Background:
- Peripheral nerve sheath tumors (PNSTs) are typically benign neurogenic neoplasms.
- Common types include schwannomas and neurofibromas, often sporadic but linked to genetic syndromes like neurofibromatosis.
- Radiation exposure is an occasional risk factor for these tumors and their malignant variants.
Related Concept Videos
Cancers Originate from Somatic Mutations in a Single Cell
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancers Originate from Somatic Mutations in a Single Cell
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...

