Cocaine-induced multifocal leukoencephalopathy: A case report and literature review

Cocaine use is associated various complications such as hemorrhagic and ischemic stroke. Another rarely reported complication is cocaine-induced multiple leukoencephalopathy. We report the case of an 18-year-old woman, without any medical history who presented with cocaine-induced multifocal leukoencephalopathy. The patient was treated with intravenous methylprednisolone and showed partial clinical improvement. Initially considered as a consequence of the drug's toxic effects, this condition has more recently been linked to levamisole, a cocaine adulterant known to cause similar cases of multiple leukoencephalopathy.