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NNI Nanoinformatics Conference 2023: Movement Toward a Common Infrastructure for Federal nanoEHS Data Computational
Holly M Mortensen1, Jaleesia D Amos2, Thomas E Exner3
1Public Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC USA.
A conference focused on nanoinformatics infrastructure for nano Environmental Health and Safety (nanoEHS) data brought together U.S. and EU stakeholders. Key recommendations include improving data standards and establishing a public data-sharing platform for nanoEHS research.
Area of Science:
- Nanotechnology
- Environmental Health and Safety (EHS)
- Informatics
- Data Science
Background:
- The National Nanotechnology Initiative (NNI) hosted a Nanoinformatics Conference aligning with the Year of Open Science.
- The conference involved U.S. and European Union (EU) stakeholders to discuss nanoinformatics infrastructure.
- This event preceded the U.S.-EU COR meeting on November 15th, 2023, in Washington, D.C.
Purpose of the Study:
- To discuss progress in developing common nanoinformatics infrastructure between the U.S. and EU.
- To highlight strengths and weaknesses of individual nanoinformatics database projects.
- To identify recommendations and next steps for a U.S. nano Environmental Health and Safety (nanoEHS) common infrastructure.
Main Methods:
- Discussions on current nanoinformatics database projects and their attributes.
- Identification of critical areas for a U.S. federal consortium effort in nanoEHS data.
- Consideration of perspectives from modelers, end-users, risk-assessors, and regulators.
Main Results:
- Improved data standards for reporting and storage were identified as initial priorities.
- Key areas for future development include data format evaluation, user perspectives, and a public data-sharing forum.
- The need for integration with new data types (e.g., micro/nano plastics) and interoperability with other data (e.g., adverse outcome pathways) was highlighted.
Conclusions:
- Continued U.S.-EU collaboration is crucial for developing shared or interoperable nanoEHS infrastructure.
- Addressing identified gaps, such as a public data repository and diverse user perspectives, is critical for progress.
- Standardization and interoperability are essential for effective nanoEHS data management and research.
