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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
19.8K
Musculoskeletal involvement in systemic sclerosis
Ewa Wielosz1, Marcin Grzegorz Hyła2
1Department of Rheumatology, Systemic Connective Tissue Diseases and Internal Diseases, Medical University of Lublin, Poland.
Reumatologia
|October 9, 2024
Summary
Systemic sclerosis (SSc) significantly impacts the musculoskeletal system in 40-90% of patients, causing pain, arthritis, and contractures. Understanding SSc
Area of Science:
- Rheumatology
- Immunology
- Connective Tissue Diseases
Background:
- Systemic sclerosis (SSc) is a complex multi-organ autoimmune disease.
- Musculoskeletal complications affect 40-90% of SSc patients, impacting bones, joints, muscles, and tendons.
Purpose of the Study:
- To review the spectrum of musculoskeletal involvement in Systemic Sclerosis.
- To highlight the impact of these complications on patient quality of life and disability.
Main Methods:
- Literature review focusing on musculoskeletal manifestations in Systemic Sclerosis.
- Analysis of common symptoms and osteo-articular changes.
Main Results:
- Common symptoms include arthralgia, arthritis, myalgia, myositis, tendinitis, acro-osteolysis, and calcinosis.
- Hand involvement frequently leads to contractures, significantly reducing quality of life and causing disability.
Conclusions:
- A deeper understanding of the etiology of SSc-related musculoskeletal changes is crucial.
- This knowledge may pave the way for novel therapeutic strategies to improve patient outcomes and reduce disability.
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