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Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis

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Published on: January 4, 2019

Postprocedure protocols after intraarticular orthobiologic injections-A scoping review.

Ryan C Kruse¹, Kristina D Rossmiller², Timothy R Fleagle³

¹Department of Orthopedics and Rehabilitation, University of Iowa Sports Medicine, Iowa City, Iowa, USA.

PM & R : the Journal of Injury, Function, and Rehabilitation

|October 9, 2024

Summary

Orthobiologic treatments for osteoarthritis show varied results due to inconsistent post-procedure care reporting. Standardizing post-orthobiologic protocols is crucial for future research and clinical application in osteoarthritis management.

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Area of Science:

Orthopedics
Regenerative Medicine

Background:

Osteoarthritis affects 500 million globally, posing a significant health burden.
Orthobiologics are explored for osteoarthritis symptom and disease modification.
Heterogeneity in orthobiologic treatment outcomes is noted in current literature.

Purpose of the Study:

To review the literature on orthobiologics for osteoarthritis.
To critically evaluate the reporting of postorthobiologic protocols in these studies.

Main Methods:

Scoping review of 200 identified studies meeting inclusion criteria.
Analysis of reported postorthobiologic protocols, including rehabilitation, weight-bearing restrictions, and medication use.

Main Results:

37.5% of studies omitted postorthobiologic protocols.
Only 38.4% detailed rehabilitation, 21.6% mentioned weight-bearing restrictions.
Medication restrictions (NSAIDs, corticosteroids) were more consistently reported than physical protocols.

Conclusions:

Significant inconsistency exists in reporting postorthobiologic protocols.
This heterogeneity may explain varied treatment outcomes.
Standardized reporting of postorthobiologic care is needed for future osteoarthritis research.