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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Management of iatrogenic ascending aortic dissection after percutaneous intervention of chronic total occlusion
Ahmad Safdar1, Laura Young1, Jaikirshan Khatri2
1Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Insights
Iatrogenic ascending aortic dissection is a rare but serious complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). Conservative management is often successful, avoiding urgent surgery.
Area of Science:
- Cardiovascular Interventions
- Interventional Cardiology
- Aortic Complications
Background:
- Iatrogenic ascending aortic dissection is a rare complication following percutaneous coronary intervention (PCI) for chronic total occlusion (CTO).
- Understanding the incidence and management of this complication is crucial for patient safety.
Purpose of the Study:
- To highlight the prevalence of iatrogenic ascending aortic dissection after CTO PCI.
- To review conservative management strategies for this complication.
Main Methods:
- Retrospective analysis of patients undergoing CTO PCI at a single medical center (2020-2022).
- Data sourced from the Prospective Global Registry for the Study of CTO database.
Main Results:
- Six cases of iatrogenic ascending aortic dissection occurred in 318 patients.
- Causes included guiding catheter trauma, injection techniques, and balloon rupture.
- Two patients underwent IVUS-guided stenting; all received conservative management with no urgent surgery.
Conclusions:
- CTO PCI has a higher complication rate, including aortic dissection, than non-CTO PCI.
- Conservative management is effective for stable patients; formal imaging is recommended.
- Outcomes for stable coronary disease patients with dissection appear better than in acute coronary syndrome.
Background:
This study highlights the prevalence and conservative management strategies of iatrogenic ascending aortic dissection after percutaneous intervention (PCI) of chronic total occlusion (CTO).
Methods:
Retrospective analysis on patients who underwent CTO PCI from one medical center from 2020 to 2022 was performed by two operators. Data was obtained from the Prospective Global Registry for the Study of CTO database.
Results:
Out of 318 patients, there were six reported cases of iatrogenic ascending aortic dissection. The causes of dissection included guiding catheter trauma, antegrade injection, two retrograde injection, and two cases of balloon rupture after lithotripsy. IVUS-guided stenting of the coronary back to the origin to seal the entry of the dissection flap occurred in two patients. All patients had a conservative management approach. No patient had to undergo urgent surgery.
Conclusion:
While the incidence remains rare, complications, including aortic dissection, are more frequent in CTO PCI as compared to non-CTO PCI. IVUS can be used to complete coronary intervention so long as the patient remains clinically and hemodynamically stable. Patients should have formal imaging with either transesophageal echocardiogram or computed tomography angiography. The outcomes of patients who experience iatrogenic aortic dissection during CTO PCI with stable coronary disease seem to be better than in patients with acute coronary syndrome.
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