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Risk Factors Associated With Exaggerated Blood Pressure Response at the Time of Exercise Treadmill Stress Test
Vasiliki Katsi1, Nikolaos Ioakeimidis1, Yannis Dimitroglou1
1Department of Cardiology, Hippokration Hospital, National and Kapodistrian University of Athens, Athens, Greece.
American Journal of Hypertension
|October 9, 2024
Summary
Exaggerated blood pressure response (EBPR) during exercise stress testing (EST) is linked to hypertension and cardiovascular events. Key predictors include middle age, elevated resting blood pressure, smoking, and family history, guiding early intervention.
Area of Science:
- Cardiology
- Preventive Medicine
- Exercise Physiology
Background:
- Exaggerated blood pressure response (EBPR) during exercise stress testing (EST) is a potential indicator of future hypertension and cardiovascular events.
- Understanding clinical and resting parameters associated with EBPR is crucial for risk stratification.
Purpose of the Study:
- To identify clinical and resting exercise stress testing parameters associated with an increased likelihood of exaggerated blood pressure response.
- To evaluate the predictive value of these parameters for cardiovascular risk.
Main Methods:
- Analysis of 14,073 patients without known cardiovascular disease who underwent treadmill EST.
- Multivariate analysis to identify independent risk factors for EBPR.
Main Results:
- The prevalence of arterial hypertension was 44%, with 24% of patients exhibiting EBPR.
- Independent risk factors for EBPR included middle age (40-60 years), resting BP >130/80 mmHg, hypertension history, smoking, and family history of coronary artery disease.
- Elevated resting BP (>130/80 mmHg) significantly increased EBPR likelihood across all age groups and in hypertensive patients, irrespective of treatment.
Conclusions:
- EBPR during EST has diagnostic and prognostic value.
- Clinical and resting hemodynamic parameters predicting EBPR are targets for lifestyle modification and early intervention.
- Identifying individuals at risk for EBPR can help reduce hypertension and cardiovascular risk factors.
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