COVID-19 Pandemic Impact on Uro-Oncological Disease Outcomes at a German Referral Center
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.The COVID-19 pandemic did not significantly alter uro-oncologic surgical activity or pathological outcomes. However, a lower pathological tumor stage for renal cancer and a higher age at diagnosis for penile cancer were observed post-pandemic.
Area Of Science
- Uro-oncology
- Surgical Oncology
- Epidemiology
Background
- The COVID-19 pandemic significantly impacted healthcare systems globally, potentially affecting cancer care delivery and patient outcomes.
- Assessing the pandemic's influence on uro-oncologic procedures and pathological findings is crucial for understanding healthcare system resilience.
Purpose Of The Study
- To evaluate changes in referral patterns and pathological outcomes for uro-oncologic cases.
- To compare clinical and pathological data from cancer surgeries before, during, and after the COVID-19 pandemic.
- To analyze trends in specific uro-oncologic procedures at a university medical center.
Main Methods
- Retrospective analysis of data from 2018 to 2023, encompassing 212 radical prostatectomies (RP), 157 radical cystectomies (RCs), 36 radical nephroureterectomies (RNUs), 133 partial nephrectomies (PNs), 160 radical nephrectomies (RNs), 93 orchifunicolectomies, and 39 penile cancer surgeries.
- Patient data were categorized into three periods: pre-pandemic (2018-Feb 2020), during the pandemic (Mar 2020-Mar 2022), and post-pandemic (Apr 2022-Feb 2023).
- Comparison of pathological features, tumor stage, age at diagnosis, and length of stay (LOS) across these periods.
Main Results
- No significant differences in main pathological features were observed for radical prostatectomy (RP), radical nephroureterectomy (RNU), orchifunicolectomy, or penile surgeries.
- A lower pathological tumor stage was noted for radical nephrectomies (RN) in the post-pandemic period (p < 0.05).
- Penile cancer patients were diagnosed at a higher age during the pandemic (p < 0.05), without impacting pathological stage or lymph node involvement. A reduced LOS for orchifunicolectomy was observed during the pandemic (p < 0.05).
Conclusions
- Uro-oncologic surgical activity and pathological features remained stable at the institution throughout the COVID-19 pandemic.
- The study identified a significant decrease in pathological tumor stage for renal cancer post-pandemic.
- Higher age at diagnosis for penile cancer during the pandemic and a shorter length of stay for orchifunicolectomy were notable findings.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...