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Published on: July 19, 2018
The Art of Ultrafiltration, from Pump to Peritoneum
1Division of Nephrology, Hypertension and Renal Transplantation, University of Florida, Gainesville, Florida, USA.
Background:
Heart failure remains a significant public health burden given its prevalence, morbidity, mortality as well its untoward financial consequences.
Summary:
The assessment of congestion and its treatment are integral in heart failure pathophysiology and outcomes. Renal venous congestion and its suboptimal response to diuretic-based and novel pharmacological therapeutic regimens have thus positioned ultrafiltration as a promising therapeutic option for patients with acute decompensated heart failure. As a corollary, peritoneal dialysis has had success establishing itself as a relevant therapeutic option for chronic cardiorenal syndrome in patients with heart failure.
Key Messages:
Herein, we will discuss the pathophysiologic basis of ultrafiltration and peritoneal dialysis in heart failure with a review of the relevant clinical trials on safety and efficacy profiles in these patient populations.
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