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Plant-derived biomass-based hydrogels for biomedical applications
Tushuai Li1, Wenxue Sun2, Da Qian3
1School of Biology and Food Engineering, Changshu Institute of Technology, Suzhou 215500, PR China.
Trends in Biotechnology
|October 9, 2024
Summary
Plant-derived biomass hydrogels offer affordable, biocompatible solutions for biomedicine. Challenges remain in matching human tissue performance, requiring further research into biosafety and material limitations.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Biomedical Engineering
Background:
- Plant-derived biomass hydrogels are increasingly utilized in biomedical applications due to their cost-effectiveness, availability, and biocompatibility.
- Significant challenges exist in developing these hydrogels to precisely mimic the complex structure, function, and performance of human tissues.
Purpose of the Study:
- To review major contributions in the field of plant-derived biomass hydrogels for biomedical applications.
- To discuss the fundamental concepts, types of biomass hydrogels (cellulose, hemicellulose, lignin), and their biosafety evaluations.
Main Methods:
- Comprehensive literature review of scientific contributions related to plant-derived biomass hydrogels.
- Analysis of basic principles, material compositions (cellulose, hemicellulose, lignin), and biosafety/toxicity assessments.
Main Results:
- Summarizes key advancements in utilizing cellulose, hemicellulose, and lignin for hydrogel fabrication.
- Provides an in-depth discussion on the biosafety and toxicity profiles of these biomass-based hydrogels.
Conclusions:
- Highlights ongoing scientific debates and identifies critical obstacles hindering the widespread biomedical application of biomass-based hydrogels.
- Emphasizes the need for continued research to overcome limitations in achieving desired tissue-mimicking properties and ensuring biosafety.

