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Plant-derived biomass-based hydrogels for biomedical applications.

Tushuai Li1, Wenxue Sun2, Da Qian3

  • 1School of Biology and Food Engineering, Changshu Institute of Technology, Suzhou 215500, PR China.

Trends in Biotechnology
|October 9, 2024
PubMed
Summary

Plant-derived biomass hydrogels offer affordable, biocompatible solutions for biomedicine. Challenges remain in matching human tissue performance, requiring further research into biosafety and material limitations.

Keywords:
biomassbiomedical applicationsbiosafety and toxicityfundamental principleshydrogels

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Biomedical Engineering

Background:

  • Plant-derived biomass hydrogels are increasingly utilized in biomedical applications due to their cost-effectiveness, availability, and biocompatibility.
  • Significant challenges exist in developing these hydrogels to precisely mimic the complex structure, function, and performance of human tissues.

Purpose of the Study:

  • To review major contributions in the field of plant-derived biomass hydrogels for biomedical applications.
  • To discuss the fundamental concepts, types of biomass hydrogels (cellulose, hemicellulose, lignin), and their biosafety evaluations.

Main Methods:

  • Comprehensive literature review of scientific contributions related to plant-derived biomass hydrogels.
  • Analysis of basic principles, material compositions (cellulose, hemicellulose, lignin), and biosafety/toxicity assessments.

Main Results:

  • Summarizes key advancements in utilizing cellulose, hemicellulose, and lignin for hydrogel fabrication.
  • Provides an in-depth discussion on the biosafety and toxicity profiles of these biomass-based hydrogels.

Conclusions:

  • Highlights ongoing scientific debates and identifies critical obstacles hindering the widespread biomedical application of biomass-based hydrogels.
  • Emphasizes the need for continued research to overcome limitations in achieving desired tissue-mimicking properties and ensuring biosafety.