Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiopulmonary Resuscitation IV: Pharmacological Management

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...

Cardiopulmonary Resuscitation III: AED Use

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...

Cardiopulmonary Resuscitation I: Adult

Cardiopulmonary Resuscitation I: Adult

Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...

Introduction Cardiac Emergencies

Introduction Cardiac Emergencies

Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...

Cardiac Action Potential

Cardiac Action Potential

Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials

Correlation between ECG and Cardiac Cycle

Correlation between ECG and Cardiac Cycle

The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Improving outcomes of patients with venovenous extracorporeal membrane oxygenation.

Perfusion·2026

Same author

Successful ECPR and early surgical repair in STEMI complicated by left ventricular free-wall rupture.

Perfusion·2026

Same author

Early colonoscopy for detection of colon ischemia after extracorporeal cardiopulmonary resuscitation.

Intensive care medicine·2026

Same author

Recommendations in Extracorporeal Cardiopulmonary Resuscitation Post Resuscitation Care Via An International, Modified Delphi Approach.

Journal of the American Heart Association·2026

Same author

Defining a national standard for ECMO emergency care.

Intensive care medicine·2026

Same author

Navigating end-of-life decision-making on ECLS discontinuation in children: insights from the international ENSURE survey.

European journal of pediatrics·2025

Same journal

[Modern therapy of pulmonary embolism with PERT and EKOS: an advantage also for in-hospital time?]

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

Same journal

[Extracorporeal immunomodulation in sepsis : Role, limits, and perspectives of adjuvant blood purification therapies].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

Same journal

[Invasive mechanical ventilation: indications and alternatives : Systematic evaluation of the evidence and recommendations for clinical practice from the S3 guidelines "invasive mechanical ventilation and the use of extracorporeal procedures in acute respiratory failure"].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

Same journal

[Out-of-hospital cardiac arrest : Current recommendations along the chain of survival and patient management].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

Same journal

[Videolaryngoscopic endotracheal intubation during out-of-hospital cardiac arrest from the perspective of paramedics : Training requirements and subjective procedural confidence-results of an anonymous cross-sectional survey].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

Same journal

[The Freiburg concept of the "Neurological Emergency Receiving Team (NERT)" : Concept for structuring of time-critical courses of action for patients with a predominant disability problem with an interdisciplinary and interprofessional emergency team in the nontraumatological resuscitation room].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 11, 2025

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

ECPR-the evolving role in cardiac arrest.

Alexander Supady¹

¹Interdisciplinary Medical Intensive Care, Medical Center-University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany. alexander.supady@uniklinik-freiburg.de.

Medizinische Klinik, Intensivmedizin Und Notfallmedizin

|October 9, 2024

Summary

This summary is machine-generated.

Extracorporeal cardiopulmonary resuscitation (ECPR) uses venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiac arrest. Specialized ECPR centers and trained teams improve survival for select patients.

Keywords:

Cardiopulmonary arrest Extracorporeal cardiopulmonary resuscitation Extracorporeal life support Return of spontaneous circulation Venoarterial extracorporeal membrane oxygenation

More Related Videos

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest

Published on: January 5, 2018

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Jun 11, 2025

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest

Published on: January 5, 2018

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

Area of Science:

Cardiology
Critical Care Medicine
Emergency Medicine

Background:

Extracorporeal cardiopulmonary resuscitation (ECPR) involves venoarterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiac arrest.
ECPR is increasingly used but not standard care, requiring careful patient selection due to significant risks.

Purpose of the Study:

To review the evolving role and optimal implementation of ECPR.
To highlight the importance of specialized centers, training, and integrated systems for ECPR.
To discuss patient selection criteria and potential complications.

Main Methods:

Review of recent randomized controlled trials and clinical practice guidelines.
Analysis of factors influencing ECPR outcomes, including caseload and team expertise.
Discussion of ECPR-associated complications and their management.

Main Results:

Randomized trials support ECPR within integrated systems centered around specialized ECPR centers.
Higher ECPR caseloads correlate with improved patient survival.
Continuous training is crucial for maintaining evidence-based ECPR quality.

Conclusions:

ECPR can enhance survival in select refractory cardiac arrest patients when delivered by expert teams in specialized centers.
Integrated pre-hospital and intra-hospital emergency care systems are vital for successful ECPR implementation.
Ongoing research and evolving selection criteria are essential for optimizing ECPR use.