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A complex case of bacterial pericarditis caused by a new pathogenic agent

Joana Lima Lopes1, Daniel Candeias Faria1, Bárbara Flor-de-Lima2

  • 1Cardiology Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.

GMS Infectious Diseases
|October 10, 2024
PubMed

Insights

Dermabacter hominis, a skin bacterium, can cause opportunistic infections. This case highlights its rare but aggressive presentation in pericardial fluid, leading to infectious bacterial pericarditis.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Cardiology

Background:

  • Dermabacter hominis is a gram-positive, facultative anaerobic bacterium commonly colonizing human skin.
  • It is known to cause opportunistic infections, primarily in immunocompromised individuals.
  • Previously reported infections involve bone, joints, eyes, and devices like peritoneal dialysis catheters and vascular grafts.

Observation:

  • This study reports the first documented case of Dermabacter hominis isolated from pericardial fluid.
  • The patient presented with infectious bacterial pericarditis.
  • The clinical course was aggressive with a poor outcome.

Findings:

  • Dermabacter hominis can be an etiological agent of infectious bacterial pericarditis.
  • The bacterium's presence in pericardial fluid indicates a potential for severe, invasive infections.
  • This contrasts with the generally favorable outcomes reported for other D. hominis infections.

Implications:

  • This case expands the spectrum of clinical manifestations attributed to Dermabacter hominis.
  • It underscores the importance of considering less common pathogens in severe infections, particularly pericarditis.
  • Further research may be needed to understand the pathogenic mechanisms and optimal treatment strategies for invasive D. hominis infections.
Keywords:
Dermabacter hominisaggressive agentinfectious pericarditispericardiectomy

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