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Updated: Jul 10, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
Published on: October 5, 2009
Three dimensional-printed artificial disc replacement for single-level cervical spondylosis: a cohort study
Xiao-Bo Zhang1, Zilin Gao1, Xin Yao1
1Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.
3D-printed artificial discs offer a clinically effective alternative to anterior cervical discectomy and fusion (ACDF) for cervical spondylosis. This innovative approach demonstrates comparable clinical outcomes with improved range of motion and reduced adjacent segment disease.
Area of Science:
- Orthopedics
- Biomaterials
- Spine Surgery
Background:
- Cervical spondylosis is a degenerative condition affecting the cervical spine.
- Anterior cervical discectomy and fusion (ACDF) is a common surgical treatment.
- Limitations of ACDF include potential adjacent segment disease and reduced range of motion.
Purpose of the Study:
- To compare the clinical efficacy of 3D-printed artificial discs with ACDF for treating single-level cervical spondylosis.
- To evaluate patient outcomes, including clinical symptoms and radiological effects.
Main Methods:
- Retrospective analysis of 73 patients with single-level cervical spondylosis.
- Patients were divided into ACDF (38) and 3D-printed artificial disc (CADR) (35) groups.
- Clinical outcomes assessed using VAS, JOA, and NDI scores. Radiological outcomes assessed using ROM tests.
Main Results:
- Both ACDF and CADR groups showed significant improvement in clinical symptoms with similar efficacy.
- The CADR group demonstrated a significantly better postoperative range of motion (ROM) compared to the ACDF group (P=0.003).
- The CADR group had a lower incidence of adjacent segment disease (ASD) (P=0.032) and less intraoperative blood loss.
Conclusions:
- 3D-printed artificial discs are clinically effective for single-level cervical spondylosis.
- This approach offers advantages over ACDF, including better maintenance of cervical ROM and a lower risk of ASD.
- 3D-printed discs represent a promising alternative for cervical spondylosis treatment.
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