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Transient vertical diplopia following ibuprofen intake: a case report
Shalom Haggiag1, Luca Prosperini2, Federico Sadun3
1Department of Neuroscience, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy. neuroshalom@hotmail.com.
Abstract:
Ibuprofen, a commonly used over-the-counter medication, is widely recognized for its effective pain relief properties but is also associated with various adverse effects, including rare ocular and neurological manifestations. We report a case of a 27-year-old male who experienced transient vertical diplopia following a standard ibuprofen dosage for back pain. Symptoms resolved promptly upon discontinuation of the drug, with normal findings on extensive clinical and laboratory evaluations. The clinical presentation, suggestive of skew deviation, implies central toxicity. This case underscores the potential for diplopia associated with NSAIDs like ibuprofen to be underdiagnosed and offers valuable insights into the central toxicity of ibuprofen. Further research is warranted to elucidate the underlying mechanisms and optimize patient care in similar scenarios.
Insights
Ibuprofen, a common pain reliever, can rarely cause temporary double vision (diplopia) due to central nervous system effects. This case highlights the importance of considering NSAID-induced neurological issues.
Area of Science:
- Neuroscience
- Ophthalmology
- Pharmacology
Background:
- Ibuprofen is a widely used nonsteroidal anti-inflammatory drug (NSAID) for pain relief.
- While generally safe, NSAIDs can rarely cause neurological and ocular adverse effects.
Observation:
- A 27-year-old male presented with transient vertical diplopia after taking ibuprofen for back pain.
- The diplopia resolved spontaneously after discontinuing ibuprofen.
- Clinical and laboratory evaluations were unremarkable.
Findings:
- The patient's symptoms were suggestive of a skew deviation, indicating potential central nervous system toxicity.
- This case suggests that NSAID-associated diplopia may be underdiagnosed.
Implications:
- This case highlights a rare but significant neurological side effect of ibuprofen.
- Further research is needed to understand the mechanisms of ibuprofen's central toxicity.
- Clinicians should consider NSAID-induced neurological effects in patients presenting with diplopia.
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