Reliability of the risk of bias assessment in randomized controlled trials for nursing: A cross-sectional study
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View abstract on PubMed
Summary
This summary is machine-generated.Disagreements in risk of bias assessments for nursing randomized controlled trials (RCTs) varied widely. Inconsistent information extraction from RCTs was the primary cause of these discrepancies in systematic reviews.
Area Of Science
- Nursing Research
- Evidence Synthesis
- Methodology
Background
- Discrepancies in risk of bias (RoB) assessments undermine the credibility of systematic reviews (SRs).
- No prior studies have specifically evaluated the reliability of RoB assessments within nursing research.
Purpose Of The Study
- To quantify the extent and identify the causes of disagreements in RoB assessments.
- Focus on randomized controlled trials (RCTs) that appear in multiple Cochrane reviews within the nursing field.
Main Methods
- Secondary data analysis utilizing existing research reports.
- Included RCTs that were part of more than one nursing Cochrane review.
- Analyzed disagreement rates and investigated underlying reasons.
Main Results
- Twenty-three RCTs were identified across multiple reviews.
- Agreement varied significantly, from 36.84% for selective reporting to 91.30% for random sequence generation.
- Poor agreement was noted for blinding of participants/personnel (50.00%), blinding of outcome assessment (58.82%), and incomplete outcome data (66.67%).
- Incomplete or differing information extraction from RCTs was the main driver of disagreements.
Conclusions
- The reliability of RoB assessments in nursing SRs is inconsistent.
- Emphasizes the need for more comprehensive and accurate data collection from RCTs during SR conduct.
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