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Updated: Jun 10, 2025

Characterization and Functional Prediction of Bacteria in Ovarian Tissues
Published on: October 23, 2021
Gut and oral microbiota in gynecological cancers: interaction, mechanism, and therapeutic value
Jian Wu1, Jiarui Li2, Meina Yan3
1Department of Clinical Laboratory, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, China. wujianglinxing@163.com.
Abstract:
Gynecologic cancers develop from the female reproductive organs. Microbial dysbiosis in the gut and oral cavity can communicate with each other through various ways, leading to mucosal destruction, inflammatory response, genomic instability, and ultimately inducing cancer and worsening. Here, we introduce the mechanisms of interactions between gut and oral microbiota and their changes in the development of gynecologic tumors. In addition, new therapeutic approaches based on microbiota modulation are discussed.
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