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Factors associated with suboptimal adherence to antihypertensive medication: Cross-sectional study using nationally
Sangyong Jo1, Taegyu Um2, Jihye Shin2
1Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.
Heliyon
|October 11, 2024
Summary
Suboptimal adherence to antihypertensive medication is a significant issue in hypertension management. This study identified factors linked to non-treatment and non-adherence in Korean patients, highlighting the need for tailored interventions.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Suboptimal adherence to antihypertensive medication poses a major challenge in blood pressure control.
- Limited research exists on suboptimal adherence to hypertension treatment, particularly within the Korean population.
Purpose of the Study:
- To investigate factors associated with suboptimal adherence to antihypertensive medication, encompassing both non-treatment and non-adherence.
- To characterize non-adherent and non-treatment hypertensive patient groups in Korea.
Main Methods:
- Utilized data from the Korea National Health and Nutrition Examination Survey (KNHANES) spanning 2007-2021.
- Classified participants into adherent, non-adherent, and non-treatment groups based on self-reported antihypertensive medication use.
- Employed multivariable adjusted logistic regression analysis to identify associations between suboptimal adherence and covariates.
Main Results:
- The study included 14,903 participants: 13,831 (92.8%) adherent, 460 (3.1%) non-adherent, and 612 (4.1%) non-treatment.
- Factors associated with receiving treatment included age, hypertension duration, diabetes, dyslipidemia, and elevated hemoglobin levels.
- Older age, longer hypertension duration, and comorbidities like diabetes mellitus and ischemic heart disease were linked to adherence.
Conclusions:
- This research provides insights into the characteristics of non-adherent and non-treatment hypertensive patients in Korea.
- Findings underscore the necessity for developing and implementing individualized health interventions to improve medication adherence and blood pressure control.
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