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Factors associated with suboptimal adherence to antihypertensive medication: Cross-sectional study using nationally

Sangyong Jo1, Taegyu Um2, Jihye Shin2

  • 1Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.

Heliyon
|October 11, 2024
PubMed

Insights

Suboptimal adherence to antihypertensive medication is a significant issue in hypertension management. This study identified factors linked to non-treatment and non-adherence in Korean patients, highlighting the need for tailored interventions.

Area of Science:

  • Cardiology
  • Public Health
  • Health Services Research

Background:

  • Suboptimal adherence to antihypertensive medication poses a major challenge in blood pressure control.
  • Limited research exists on suboptimal adherence to hypertension treatment, particularly within the Korean population.

Purpose of the Study:

  • To investigate factors associated with suboptimal adherence to antihypertensive medication, encompassing both non-treatment and non-adherence.
  • To characterize non-adherent and non-treatment hypertensive patient groups in Korea.

Main Methods:

  • Utilized data from the Korea National Health and Nutrition Examination Survey (KNHANES) spanning 2007-2021.
  • Classified participants into adherent, non-adherent, and non-treatment groups based on self-reported antihypertensive medication use.
  • Employed multivariable adjusted logistic regression analysis to identify associations between suboptimal adherence and covariates.

Main Results:

  • The study included 14,903 participants: 13,831 (92.8%) adherent, 460 (3.1%) non-adherent, and 612 (4.1%) non-treatment.
  • Factors associated with receiving treatment included age, hypertension duration, diabetes, dyslipidemia, and elevated hemoglobin levels.
  • Older age, longer hypertension duration, and comorbidities like diabetes mellitus and ischemic heart disease were linked to adherence.

Conclusions:

  • This research provides insights into the characteristics of non-adherent and non-treatment hypertensive patients in Korea.
  • Findings underscore the necessity for developing and implementing individualized health interventions to improve medication adherence and blood pressure control.

Keywords:
HypertensionKoreaTherapyTreatment adherence and compliance

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