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Atomically precise copper nanoclusters mediated Fenton-like reaction for cancer chemodynamic therapy
Vishal Saini1, Kartikay Tyagi1, Reena Kumari1
1Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee-247667, Uttarakhand, India. venkatesh.v@cy.iitr.ac.in.
Abstract:
We developed stable luminescent morpholine-appended copper nanoclusters CuNCs@MorMB with an ultra-small size (<3 nm) and a long emission lifetime (577 ns). They mediate a Fenton-like reaction to produce reactive hydroxyl radicals (˙OH), subsequently depleting antioxidant glutathione levels for cancer chemodynamic therapy (CDT).

