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Updated: Jun 10, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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SRF promotes long-range chromatin loop formation and stem cell pluripotency

Pavel Tsaytler1, Gaby Blaess1, Manuela Scholze-Wittler1

  • 1Department Developmental Genetics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany.

Cell Reports
|October 11, 2024
PubMed

Keywords:
CP: Molecular biologyCP: Stem cell researchCTCFNANOGOSN enhancersSOX2SRFTAD insulationchromatin loopschromatin organizationlong-range contact regulationpluripotency

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