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Updated: Jun 10, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Anaerobe-Targeted Antibiotic Therapy in the Neonatal Intensive Care Unit
Matthew B Green1, Alvaro Zevallos Barboza2, Sagori Mukhopadhyay2,3
1Rowan-Virtua School of Osteopathic Medicine, Stratford, New Jersey, USA.
Abstract:
Anaerobe-targeted antibiotic (ATA) therapy may adversely impact the developing neonatal microbiome. We describe utilization patterns, potential indications, and related outcomes of ATA therapy in neonatal intensive care units across the United States over 13 years. While overall antibiotic use decreased, ATA use was unchanged. Potentially associated indications were inconsistent.
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