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Updated: Jun 10, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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Bicyclo[2.1.1]hexanes via Intramolecular Formal (3+2)-Cycloaddition

Alexander S Harmata1, Elene Tatunashvili2,1, Abigail Chang1

  • 1Department of Chemistry, University of Michigan, 930 N University Ave, Ann Arbor, MI, 48109, United States.

Angewandte Chemie (International Ed. in English)
|October 11, 2024
PubMed
Summary

This study introduces a new method for synthesizing bicyclo[2.1.1]hexanes using a cycloaddition reaction. The resulting bicyclic imines can undergo photo-induced ring opening for stereochemical control.

Keywords:
bicyclo[2.1.1]hexanebicyclo[3.2.1]octanecycloadditioniminephotochemistry

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