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2-Mercaptobenzothiazole-derived vulcanization accelerators in urine samples from Chinese adults
Xiaoyu Wu1, Yingying Zhu2, Ruyue Guo3
1Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang 318000, PR China.
Abstract:
Studies have discovered wide presence of 2-mercaptobenzothiazole (2-MBT) and 2-MBT-derived vulcanization accelerators (MVAs) in household dust samples, suggesting that these chemicals may have been pervasive in the environment. However, despite the potential for human exposure, the presence of MVAs in human urine, a common matrix used for assessing exposure to environmental chemicals, has not been thoroughly investigated. The current study comprehensively analyzed 11 kinds of MVAs in urine samples from the recruited general population (n = 197) living in Taizhou city, China. Five kinds of MVAs were detectable in >50 % of human urine samples. This indicates the widespread exposure to these vulcanization accelerators among the general population. The predominant target analytes in human urine were 2-MBT and 2,2'-dithiobisbenzothiazole (MBTS), with the mean urinary concentrations of 2.7 ng/mL (range
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