[Calamine in the ophthalmic external treatment prescription in ancient times]

Calamine and its related medicines came into China as articles of tribute from other countries in ancient times. It was not recorded in the books of Chinese materia medica before the Song Dynasty but was widely used in ophthalmology, dermatology and traumatology and was, recorded specifically in the Ming and Qing Dynasty. This paper systematically examines the evolution of calamine herb in the archives of traditional Chinese medicine in terms of ophthalmic eternal treatment prescriptions. It was found that a total of 320 ophthalmic treatment formulas or prescriptions involved calamine, mainly finding its expression in 67 books on herbal medicines, formula and prescriptions, clinical syndrome comprehension and ophthalmic monographs. It was also found that calamine, as an important ophthalmic external medicine, had a wide range of clinical applications, covering internal and external obstructive eye diseases. Its flexibility, diverse compatibility and use in various processing are of great value and significance for in-depth exploration of its current application, its further use in ophthalmic treatment formulas or prescriptions and the redevelopment of classic formulas and prescriptions as well.