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Updated: Jun 10, 2025
06:26
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
202
Risk factors for postoperative hepatic dysfunction in overweight patients with acute type A aortic dissection
Yu Xu1, Lin-Zhuo Liu2, Hong-Qiao Lu2
1Panzhihua Central Hospital, 34 Yikang St, Panzhihua, Sichuan Province, 617000, China.
BMC Surgery
|October 12, 2024
Summary
High creatinine levels are a key risk factor for acute hepatic dysfunction after type A aortic dissection surgery in overweight patients. This finding helps predict and manage postoperative complications in this vulnerable group.
Area of Science:
- Cardiovascular Surgery
- Hepatology
- Critical Care Medicine
Background:
- Acute hepatic dysfunction (AHD) is a frequent complication following surgery for acute type A aortic dissection (ATAAD).
- Identifying predictors of AHD is crucial for improving patient outcomes after ATAAD repair.
Purpose of the Study:
- To determine the risk factors associated with the incidence of AHD post-ATAAD surgery.
- To evaluate the predictive value of identified risk factors for AHD.
Main Methods:
- Retrospective analysis of 147 patients undergoing ATAAD surgery between March 2019 and February 2021.
- Univariate and multivariate logistic regression analyses were employed to identify risk factors.
- Receiver operating characteristic (ROC) curves were utilized to assess predictive accuracy.
Main Results:
- Postoperative AHD occurred in 19.73% of patients, with a 6.12% mortality rate.
- Elevated ALT, Creatinine (Cr), and Blood Urea Nitrogen (BUN) levels were significant in univariate analysis.
- Cr was identified as an independent risk factor for AHD in overweight patients with ATAAD (OR=1.013, P=0.008), with an AUC of 0.745.
Conclusions:
- Elevated serum creatinine concentration is a significant independent risk factor for AHD in overweight patients with ATAAD.
- Cr levels demonstrate good predictive value for postoperative hepatic dysfunction in this population.
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