A chromosomal study on blood lymphocytes of patients poisoned by polychlorinated biphenyls

Chromosome studies were carried out on peripheral blood lymphocytes from 36 PCB-poisoned patients and on ten PCB-unexposed healthy controls. Nineteen out of 36 patients (52.7%) had either chromosome or chromatid aberrations, while none of the controls had. The highest percentage of cells with chromosome or chromatid aberrations in a single individual was 34.0. The blood PCB level ranged from 6.4 to 101.8 ppb, with a mean of 34.1 ppb. No correlation was observed between the level of blood PCB and the presence or absence of chromosome or chromatid aberrations.