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Diffuse large B cell non-Hodgkin lymphoma complicated with jejunal stricture and perforation
Prajjwol Luitel1, Ishwor Thapaliya1, Sujan Paudel1
1Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Introduction:
DLBCL with gastrointestinal involvement is a relatively rare form of extra-nodal lymphoma, and complications such as spontaneous perforation and jejunal stricture in this disease are even rarer.
Case Presentation:
A 45-year-old male presented with abdominal pain and vomiting. Diagnosis revealed a jejunal stricture with perforation, necessitating resection and anastomosis. Histopathology performed after surgery confirmed DLBCL, and the patient was referred for chemotherapy.
Discussion:
DLBCL with gastrointestinal involvement is uncommon and often manifests with nonspecific symptoms, leading to diagnostic delays. Treatment includes addressing both lymphoma and associated complications, with surgical intervention reserved for emergencies.
Conclusion:
Bowel perforation and jejunal stricture in non-Hodgkin's lymphoma are serious complications requiring prompt treatment to improve outcomes and reduce mortality.
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