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Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
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Perilymphatic enhancement and endolymphatic hydrops: MRI findings and clinical associations

Masumi Kobayashi1, Tadao Yoshida1, Yukari Fukunaga2

  • 1Department of Otorhinolaryngology Nagoya University Graduate School of Medicine Nagoya Japan.

Laryngoscope Investigative Otolaryngology
|October 14, 2024
PubMed
Abstract

Insights

Magnetic resonance imaging (MRI) shows significant endolymphatic hydrops (EH) in definite Meniere's disease (MD). High perilymphatic enhancement (PE) on MRI indicates active MD symptoms, including vertigo and hearing fluctuations.

Area of Science:

  • Otolaryngology
  • Radiology
  • Neuroscience

Background:

  • Meniere's disease (MD) is a disorder of the inner ear characterized by vestibular and cochlear symptoms.
  • Magnetic resonance imaging (MRI) has emerged as a valuable tool for diagnosing inner ear disorders.
  • Perilymphatic enhancement (PE) and endolymphatic hydrops (EH) are key MRI findings associated with MD.

Purpose of the Study:

  • To summarize MRI findings of PE and EH in the inner ear.
  • To correlate these findings with vestibular and cochlear symptoms in patients with Meniere's disease.

Main Methods:

  • Analysis of contrast-enhanced 3-Tesla MRI data from 508 ears of 254 patients.
  • Evaluation of endolymphatic hydrops (EH) and signal intensity ratios (SIRs) for perilymphatic enhancement (PE).
  • Correlation of imaging findings with clinical data, including Meniere's disease (MD) diagnosis, sensorineural hearing loss (SNHL), vertigo, and listening difficulties (LiD).

Main Results:

  • Ears with definite MD showed significantly higher percentages of EH in the vestibule and cochlea compared to other conditions.
  • MD and SNHL ears had significantly higher SIRs of PE than other or asymptomatic ears.
  • In definite MD patients, higher SIRs of PE correlated with recent hearing fluctuations or vertigo attacks.

Conclusions:

  • Significant EH is a major imaging diagnostic finding for definite MD.
  • High SIR of PE is a reliable indicator of MD activity, reflecting vestibular and cochlear symptom fluctuations.
  • MRI findings of EH and PE aid in the diagnosis and assessment of Meniere's disease activity.
Keywords:
Meniere's diseaseendolymphatic hydropsperilymphatic enhancement

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