Sandfly Virus Infection in Adana, Türkiye

We described the clinical and laboratory characteristics of the patients infected by sandfly viruses between August and September 2008 in Adana, Türkiye. The immunofluorescence antibody test (EUROIMMUN Medizinische Labordiagnostika AG, Lübeck, Germany) was used for diagnosis. Antibodies of immunoglobulin M (IgM) type against Cyprus and Sicily species of phleboviruses were detected in 15 patients. In one patient, IgM antibodies against Naples and Tuscany species were found to be positive. The mean age of the patients was 28, and 47% was female. The most common symptoms were myalgia, fatigue, fever, and arthralgia. The mean duration of fever was four days, and the mean duration of the symptoms was 7-10 days. The median platelet count was 137,000/mL, the median white blood cell count was 3040/mL, the median aspartate transaminase (AST) was 57 (22-1251) IU/L, the median alanine transaminase (ALT) was 71 (17-1137) IU/L, the median creatinine kinase was 314 (33-4638) IU/L, and the median lactate dehydrogenase (LDH) was 193 (111-490) IU/L. The sandfly virus infections should be differentiated from similar viral infectious diseases such as Crimean-Congo hemorrhagic fever.