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Reliability and Validity of an Ultrasound-Derived Measure for Axial Patellofemoral Alignment
Elliot M Greenberg1,2, Megan Barnes1, J Todd Lawrence1,2
1Children's Hospital of Philadelphia Sports Medicine and Performance Center, Philadelphia, Pennsylvania, USA.
Orthopaedic Journal of Sports Medicine
|October 14, 2024
Summary
Ultrasound imaging can reliably assess extensor mechanism alignment in patients with patellofemoral instability (PFI). A smaller distance between the patellar tendon and lateral trochlear ridge (MPT-LTR) in PFI patients indicates greater lateralization.
Area of Science:
- Orthopedics
- Radiology
- Biomedical Engineering
Background:
- Patellofemoral instability (PFI) assessment often uses MRI, but ultrasound (US) offers a cost-effective alternative.
- Evaluating axial extensor mechanism alignment is crucial for diagnosing PFI.
Purpose of the Study:
- To develop and validate a novel musculoskeletal ultrasound (US) measure for patellofemoral joint extensor mechanism alignment.
- To assess the reliability and construct validity of this US measure by comparing patients with and without PFI.
Main Methods:
- A cohort study compared patients with PFI (n=24) and healthy controls (n=26).
- Musculoskeletal US measured the distance between the midpoint of the patellar tendon and the lateral trochlear ridge (MPT-LTR).
- Interrater and test-retest reliability were assessed using intraclass correlation coefficients (ICC).
Main Results:
- The US-based MPT-LTR measurement demonstrated good (ICC=0.785) to excellent (ICC=0.958) reliability.
- Patients with PFI showed a significantly smaller MPT-LTR distance compared to controls in both involved and uninvolved limbs (P < .001).
- This smaller distance indicates greater lateralization of the patellar tendon relative to the trochlea in PFI patients.
Conclusions:
- The ultrasound-derived MPT-LTR distance is a reliable measure for assessing extensor mechanism alignment.
- A smaller MPT-LTR distance, indicative of greater lateralization, is associated with patellofemoral instability.

