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Published on: November 10, 2023
Crohn's disease presenting with pleural effusion: a case report
Harem K Ahmed1,2, Dilan S Hiwa1, Soran H Tahir1,3
1Scientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaymaniyah 46001, Kurdistan, Iraq.
This study details an extremely rare case of Crohn's disease (CD) presenting as isolated bilateral pleural effusion. This pulmonary manifestation, characterized by cough and chest pain, highlights the diverse and unusual ways CD can manifest.
Area of Science:
- Gastroenterology and Pulmonology
- Inflammatory Bowel Disease Research
- Clinical Case Study
Background:
- Crohn's disease (CD) is a chronic inflammatory condition.
- Extraintestinal manifestations occur in approximately 25% of CD patients.
- Pulmonary involvement in CD is uncommon, with pleural effusion being particularly rare.
Observation:
- A 43-year-old male presented with persistent dry cough, pleuritic chest pain, and dyspnea.
- Initial investigations revealed bilateral mild pleural effusion on chest CT.
- Symptoms were partially relieved by symptomatic treatment, prompting further investigation.
Findings:
- The patient exhibited symptoms suggestive of gastrointestinal involvement, including occasional black stools.
- Elevated serum calprotectin levels were detected.
- Colonoscopy confirmed a diagnosis of Crohn's disease, establishing the link to the pulmonary findings.
Implications:
- This case underscores that isolated pleural effusion, though rare, can be a pulmonary manifestation of Crohn's disease.
- Clinicians should consider CD in the differential diagnosis of unexplained pleural effusion, especially with concurrent gastrointestinal symptoms.
- The findings emphasize the need for a comprehensive diagnostic approach in patients with suspected inflammatory bowel disease and atypical symptoms.
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