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Advancements in pediatric headache
Richard N Miller1, Monica E Kim1, Muhammed Talha Gunduz1
1Department of Pediatrics.
Insights
Recent advancements in pediatric headache include updated diagnostic criteria and effective treatments. Therapies like onabotulinum toxin A and intranasal sumatriptan show promise for managing pediatric headache syndromes.
Area of Science:
- Pediatric Neurology
- Headache Medicine
- Clinical Research
Background:
- Primary headache disorders in children require updated understanding.
- International Classification of Headache Disorders 3rd edition (ICHD-3) criteria are being refined.
- Pediatric headache management necessitates evidence-based therapeutic updates.
Purpose of the Study:
- To review recent advancements in pediatric headache.
- To update clinicians on current pediatric headache research and treatment outcomes.
Main Methods:
- Review of recent studies comparing pediatric headache symptomatology with ICHD-3 criteria.
- Analysis of treatment outcomes for various pediatric headache interventions.
- Evaluation of novel therapeutic approaches including pharmacologic and toxin-based therapies.
Main Results:
- Primary stabbing headache duration may exceed previous estimates.
- Persistent posttraumatic and new daily persistent headaches share features with migraine.
- Lifestyle improvements showed no direct correlation with headache outcome, though overall improvement was noted.
- Onabotulinum toxin A and incobotulinum toxin A injections demonstrated significant headache score reduction with minimal side effects.
- Intranasal sumatriptan proved effective in reducing pain scores in emergency settings, potentially lowering costs and length of stay.
Conclusions:
- Pediatric headache syndromes exhibit evolving symptomatology and duration characteristics.
- Onabotulinum toxin A and incobotulinum toxin A injections are well-tolerated and effective.
- Emergency department administration of intranasal sumatriptan is a viable and effective treatment option for pediatric headache.
Purpose Of Review:
To provide an update on advancements in pediatric headache.
Recent Findings:
The symptomatology associated with primary headache disorders has been compared with ICHD-3 criteria. Primary stabbing headache pain lasts longer than 3 seconds in over half of patients. Persistent posttraumatic headache or new daily persistent headache have significant overlap in pain character and nonpain-related symptoms with migraine. In a large cohort with continuous headache at first follow-up, 47% reported resolution of their continuous headache and 19.4% had a 50% or greater reduction in frequency with improvements in fluid intake, sleep, not skipping meals, and exercise. There was no correlation with improved lifestyle habits and clinical outcomes despite the overall improvement. Studies noted significant improvement in headache scores with onabotulinum toxin A and incobotulinum toxin A injections with limited side effects. Intranasal sumatriptan without concurrent intravenous therapies found a clinically meaningful decrease in pain score prior to discharge with shorter lengths of stay and lower emergency department costs compared with the those who received intravenous therapies.
Summary:
Newer studies have suggested changes to symptomatology and duration of pediatric headache syndromes. Onabotulinum toxin A and incobotulinum toxin A injections, and emergency department intranasal sumatriptan are well tolerated therapies in pediatric headache.
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