Related Experiment Video
Updated: Jun 10, 2025

06:26
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
202
Ruptured aortic aneurysm in an adolescent with systemic lupus erythematosus.
Laura M Pérez1, Marianela Fiorotto1, Giselle Villarreal2
1Emergency Unit; Hospital de Pediatría S.A.M.I.C. Prof. Dr. Juan P. Garrahan, City of Buenos Aires, Argentina.
Archivos Argentinos De Pediatria
|October 14, 2024
Summary
Systemic lupus erythematosus (SLE) can rarely cause fatal aortic aneurysms in children. Early consideration of these vascular complications is crucial for pediatric patients with SLE presenting with chest pain.
Area of Science:
- Cardiovascular Medicine
- Pediatric Rheumatology
- Autoimmune Diseases
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organ systems.
- Cardiovascular complications are common in SLE, but aortic aneurysms and dissections are rare, particularly in pediatric cases.
- These vascular events carry a high mortality rate.
Related Concept Videos
Aneurysm I: Introduction
3
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
3
Aneurysm II: Clinical Manifestations and Diagnostic Studies
3
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
3
Aneurysm III: Interprofessional Care
3
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
3
Rheumatic Heart Disease I: Introduction
3
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
3
Aortic Regurgitation I: Introduction
3
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
3

