Related Experiment Video
Updated: Jun 10, 2025
Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Analysis of factors influencing refractive error in Fuchs eyes undergoing Descemet membrane endothelial keratoplasty
Jenny Chun Ling Kuo1,2, Kyong Jin Cho3,4, Muhammad Ali5
1Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Purpose:
To evaluate the accuracy of current intraocular lens (IOL) formulas and identify factors influencing mean error in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK) triple procedure, that is, DMEK combined with cataract extraction and IOL placement for concurrent Fuchs endothelial corneal dystrophy (FECD) and cataracts.
Design:
Retrospective cohort study.
Subjects:
90 eyes with FECD undergoing uncomplicated DMEK triple procedure at Wilmer Eye Institute.
Methods:
We analysed tomographic features of oedema, including loss of regular isopachs, displacement of the thinnest point of the cornea and the presence of posterior surface depression, and assessed the correlation with the prediction error.
Main Outcome Measures:
We compared the mean error (±SD) for the Barrett Universal II (BU2), Hoffer QST, Haigis-L (HL) and Barrett True K (BTK) formulas and the percentage of eyes within 0.25, 0.5 and 1 diopter (D) of error.
Results:
All formulas resulted in a mean hyperopic error, with the HL having the lowest mean error of 0.24 D (±0.97 D) and BU2 having the highest ME of 0.94 D (±0.97 D). For each additional tomographic feature of corneal oedema in the BU2 and Hoffer QST formulas, the mean hyperopic error increased by 0.38 D. For the BTK and HL formulas, the mean error increased by 0.35 D (p<0.001).
Conclusion:
The number of tomographic features of oedema can be useful in identifying eyes with higher errors in IOL calculation when performing the DMEK triple procedure for FECD.
More Related Videos
12:36A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Published on: July 22, 2022
05:46Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
