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A five-year-old boy with anaphylaxis reaction to gadolinium-based MR contrast medium: a case report

Seung Hun Woo1, Jung Bum Han1, Tae Young Ahn2

  • 1Department of Orthopedic Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, 50612, Gyeongsangnam-do, Korea.

BMC Pediatrics
|October 14, 2024
PubMed

Insights

Gadolinium-based contrast media are generally safe for MRI scans but can cause rare, severe allergic reactions like anaphylaxis. This case highlights a serious reaction in a child during a knee MRI.

Area of Science:

  • Radiology
  • Allergy and Immunology
  • Pediatric Medicine

Background:

  • Magnetic resonance imaging (MRI) is a crucial diagnostic tool in orthopedics.
  • Gadolinium-based contrast media (GBCM) enhance MRI visualization but carry a risk of adverse reactions.
  • Immediate hypersensitivity reactions to GBCM, though uncommon, can be severe.

Observation:

  • A 5-year-old boy experienced anaphylaxis after GBCM injection during a knee MRI.
  • Anaphylaxis is a life-threatening allergic reaction with symptoms including rash, breathing difficulties, and cardiovascular collapse.

Findings:

  • This case underscores the potential for severe immediate hypersensitivity reactions to GBCM, even in pediatric patients.
  • The reported incident involved a serious anaphylactic event following GBCM administration for a knee MRI.

Implications:

  • Healthcare providers should be vigilant for anaphylaxis in patients receiving GBCM, particularly children.
  • Awareness and preparedness for managing severe allergic reactions to contrast agents are essential in radiology departments.
  • Further research into risk factors and prevention strategies for GBCM-induced anaphylaxis may be warranted.
Keywords:
AnaphylaxisGadolinium-based Magnetic Resonance (MR) contrast mediaPediatricsSevere acute adverse reaction

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