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Updated: Jun 10, 2025

Preparation, Purification, and Use of Fatty Acid-containing Liposomes
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Published on: February 9, 2018

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Hybrid Protocells Based on Coacervate-Templated Fatty Acid Vesicles Combine Improved Membrane Stability with

Jessica Lee1, Fatma Pir Cakmak1, Richard Booth1

  • 1Department of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.

Small (Weinheim an Der Bergstrasse, Germany)
|October 15, 2024
PubMed
Summary

This study demonstrates robust protocell models by encapsulating coacervate droplets within fatty acid membranes. These coacervate-supported membranes resist disruption by magnesium ions, enabling essential prebiotic chemistry.

Keywords:
compartmentalizationester hydrolysislipidmagnesiummembrane permeabilitynonenzymatic catalysisphase separation

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