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Updated: Jun 10, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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Overcoming EGFR-TKI resistance by targeting the tumor microenvironment

Jinsong Zhang1, Natalie Vokes2, Man Li1

  • 1State Key Laboratory of Molecular Oncology, CAMS Key Laboratory of Translational Research on Lung Cancer, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17, Panjiayuannanli, Chaoyang District, Beijing 100021, China.

Chinese Medical Journal Pulmonary and Critical Care Medicine
|October 15, 2024
PubMed

Keywords:
Drug resistanceEpidermal growth factor receptorEpidermal growth factor receptor-tyrosine kinase inhibitorNon-small cell lung cancerTumor microenvironment

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