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Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
Sedated Colonoscopy May Not Be Beneficial For Polyp/adenoma Detection.

Home
Research Domains
Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
Sedated Colonoscopy May Not Be Beneficial For Polyp/adenoma Detection.

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Sedated Colonoscopy may not be Beneficial for Polyp/Adenoma Detection.

Jie Han^1,2, Rongrong Cao¹, Dongshuai Su¹

¹Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China.

Cancer Control : Journal of the Moffitt Cancer Center

|October 15, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Sedated colonoscopy is associated with a lower polyp/adenoma detection rate (PDR/ADR), particularly in the right colon. Further research is needed to improve the quality of sedated colonoscopies.

Keywords:

adenoma detection rate polyp detection rate sedated colonoscopy unsedated colonoscopy

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Area of Science:

Gastroenterology
Endoscopy
Clinical Research

Background:

Sedated colonoscopy is increasingly utilized for patient comfort.
The impact of sedation on polyp/adenoma detection rate (PDR/ADR) remains a subject of ongoing debate.

Purpose of the Study:

To investigate the association between sedated colonoscopy and PDR/ADR.
To analyze the effect of sedation on PDR/ADR in different colonic segments and polyp counts.

Main Methods:

Retrospective analysis of 2,275 colonoscopies (293 sedated, 1982 unsedated).
Multivariate logistic regression adjusted for confounding factors (age, gender, BMI, etc.).
Evaluation of overall, right-side, transverse, left-side, single, and multiple PDR/ADR.

Main Results:

Sedated colonoscopy was linked to significantly lower overall PDR/ADR (OR=0.640).
Reduced PDR/ADR was observed in the right colon (OR=0.591) and for single (OR=0.659) and multiple (OR=0.586) polyps/adenomas.
No significant association was found for transverse or left-side colon PDR/ADR.

Conclusions:

Sedated colonoscopy may not improve, and could potentially decrease, overall and right-side PDR/ADR.
Selective recommendation of sedated colonoscopy is suggested.
Strategies to enhance the quality of sedated colonoscopies require investigation.