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Adrenal tissue characterization using MR imaging.

G M Glazer, E J Woolsey, J Borrello

    Radiology
    |January 1, 1986
    PubMed
    Summary
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    Magnetic resonance (MR) imaging shows promise for characterizing adrenal masses. Specific MR signal intensity ratios can help distinguish adrenal adenomas from other adrenal lesions, improving diagnostic accuracy.

    Area of Science:

    • Radiology
    • Oncology
    • Endocrinology

    Background:

    • Adrenal masses require accurate characterization to guide management.
    • Distinguishing adrenal adenomas from other adrenal lesions can be challenging.
    • Magnetic resonance (MR) imaging offers advanced visualization capabilities.

    Purpose of the Study:

    • To evaluate the potential of MR imaging for adrenal tissue characterization.
    • To differentiate adrenal adenomas from non-adenomas using MR data.
    • To identify quantitative MR parameters useful for adrenal lesion diagnosis.

    Main Methods:

    • MR imaging was performed on 28 patients with 33 adrenal masses using a 0.35 T superconducting magnet.
    • Spin-echo pulse sequences were acquired at specific repetition times (TR) and echo times (TE).

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  • Both qualitative visual assessment and quantitative data (signal intensity, ratios, T1, T2) were analyzed.

    • Main Results:

    • Non-hyperfunctioning adrenal adenomas could be distinguished from non-adenomas using qualitative and quantitative MR data.
    • Adrenal lesion to liver intensity ratios at TR 0.5 sec, TE 56 msec were highly effective: adenomas had ratios < 0.83, non-adenomas > 0.83.
    • Visual assessment showed non-adenomas were often hyperintense compared to liver, unlike adenomas.

    Conclusions:

    • MR imaging demonstrates significant potential for adrenal tissue characterization.
    • Quantitative MR parameters, particularly lesion/liver intensity ratios, are valuable for diagnosing adrenal adenomas.
    • MR imaging can aid in differentiating benign adrenal adenomas from malignant or other neoplastic lesions.