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Updated: Jun 10, 2025

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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Breast implant-associated anaplastic large cell lymphoma
Lars Frich1, Robert Hermann1, Truls Ryder2
1Seksjon for rekonstruktiv og onkologisk plastikkirurgi, Kreftkirurgisk avdeling, Oslo universitetssykehus, Radiumhospitalet.
Summary
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare cancer linked to textured breast implants. Early detection and removal of the implant and capsule offer a very good prognosis.
Area of Science:
- Oncology
- Plastic Surgery
- Pathology
Background:
- Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell lymphoma.
- It is specifically associated with textured breast implants.
- BIA-ALCL can manifest as late-onset breast asymmetry or seroma.
Purpose of the Study:
- To provide a clinical review of BIA-ALCL.
- To outline diagnostic criteria for BIA-ALCL.
- To summarize treatment strategies for BIA-ALCL.
Main Methods:
- This article is a clinical review.
- It synthesizes current knowledge on BIA-ALCL diagnosis and treatment.
- Literature review of relevant studies and case reports.
Main Results:
- BIA-ALCL diagnosis should be suspected with new breast asymmetry or seroma in patients with textured implants.
- Complete removal of the implant and surrounding capsule is the primary treatment.
- Prognosis is generally excellent following surgical intervention.
Conclusions:
- BIA-ALCL is a treatable condition, particularly when diagnosed early.
- Awareness among clinicians is crucial for timely diagnosis.
- Prompt surgical management leads to favorable outcomes.

