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Updated: Jun 10, 2025
10:04
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
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Nontuberculous Mycobacterial Pulmonary Disease: Patients, Principles, and Prospects
Minh-Vu H Nguyen1, Michelle K Haas1,2, Shannon H Kasperbauer1
1Division of Mycobacterial and Respiratory Infections, Department of Medicine, National Jewish Health, Denver, Colorado, USA.
Summary
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a growing global health challenge. This review simplifies NTM-PD management by outlining key principles for diagnosis and patient-centered, pathogen-directed therapy.
Area of Science:
- Pulmonology
- Infectious Diseases
- Microbiology
Background:
- Nontuberculous mycobacterial pulmonary disease (NTM-PD) incidence is rising globally.
- Management of NTM-PD is complex due to over 190 NTM species requiring tailored multidrug regimens.
- Existing guidelines offer comprehensive evidence but the field's breadth remains challenging.
Purpose of the Study:
- To distill the complex field of NTM-PD into applicable principles.
- To provide clinicians and patients with a clearer understanding of NTM-PD management.
- To highlight key aspects including presentation, diagnosis, care principles, and future prospects.
Main Methods:
- Narrative review of current literature and guidelines.
- Synthesis of evidence-based information on NTM-PD.
- Focus on principles applicable across most NTM species.
Main Results:
- Established principles for patient-centered care in NTM-PD.
- Outlined principles for pathogen-directed therapy.
- Detailed presentation and diagnostic considerations for NTM-PD.
Conclusions:
- Simplifying NTM-PD management through core principles is crucial.
- Patient-centered care and pathogen-directed therapy are vital for effective NTM-PD treatment.
- Further advancements are needed to address the complexity of NTM-PD.
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